Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6567927 | 0.90 | BTN3A1 (0.58) | BTN3A1POLBGAACYP2C19PLAU | |
| SCHEMBL17465458 | 0.89 | ELANE (0.55) | BTN3A1PLAUELANEALDH1A1PRTN3 | |
| SCHEMBL19685666 | 0.89 | ELANE (0.55) | BTN3A1PLAUELANEALDH1A1PRTN3 | |
| SCHEMBL24148685 | 0.82 | BTN3A1 (0.51) | BTN3A1POLBGAACYP2C19PLAU | |
| SCHEMBL30337877 | 0.80 | GAA (0.48) | POLBGAACYP2C19KMT2AALDH1A1 | |
| SCHEMBL28986510 | 0.80 | GAA (0.48) | POLBGAACYP2C19KMT2AALDH1A1 | |
| SCHEMBL18973549 | 0.79 | BTN3A1 (0.60) | BTN3A1PLAUELANEKMT2AALDH1A1 | |
| SCHEMBL24505391 | 0.79 | BTN3A1 (0.60) | BTN3A1PLAUELANEKMT2AALDH1A1 | |
| SCHEMBL12621321 | 0.78 | BTN3A1 (0.44) | BTN3A1PLAUELANEPRTN3 | |
| SCHEMBL13921734 | 0.77 | ELANE (0.55) | BTN3A1PLAUELANEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404694-A1 | NUCLEOSIDE COMPOUNDS IN HCV | GLAXO GROUP LIMITED (GB) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003000713-A1 | NUCLEOSIDE COMPOUNDS IN HCV | GLAXO GROUP LIMITED (GB) | 2003-01-03 | — | — | WO | disclosed |