Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTN3A1 | O00481 | 4/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24148685 | 0.92 | BTN3A1 (0.51) | BTN3A1ELANEPOLBGAACYP2C19 | |
| SCHEMBL18973549 | 0.90 | BTN3A1 (0.60) | BTN3A1ELANEPRTN3PLAUKMT2A | |
| SCHEMBL24505391 | 0.90 | BTN3A1 (0.60) | BTN3A1ELANEPRTN3PLAUKMT2A | |
| SCHEMBL6567925 | 0.90 | BTN3A1 (0.48) | BTN3A1ELANEPOLBGAACYP2C19 | |
| SCHEMBL18973481 | 0.86 | BTN3A1 (0.55) | BTN3A1ELANEGAAPRTN3PLAU | |
| SCHEMBL18973564 | 0.86 | BTN3A1 (0.55) | BTN3A1ELANEPRTN3PLAUKMT2A | |
| SCHEMBL18973567 | 0.86 | BTN3A1 (0.55) | BTN3A1ELANEPRTN3KMT2AALDH1A1 | |
| SCHEMBL18973471 | 0.86 | TP53 (0.56) | BTN3A1ELANEGAAPRTN3KMT2A | |
| SCHEMBL12094256 | 0.85 | BTN3A1 (0.56) | BTN3A1ELANEPRTN3PLAUKMT2A | |
| SCHEMBL22066287 | 0.83 | BTN3A1 (0.52) | BTN3A1ELANEPRTN3KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404694-A1 | NUCLEOSIDE COMPOUNDS IN HCV | GLAXO GROUP LIMITED (GB) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003000713-A1 | NUCLEOSIDE COMPOUNDS IN HCV | GLAXO GROUP LIMITED (GB) | 2003-01-03 | — | — | WO | disclosed |