Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPIA | P62937 | 2/20 | 0.58 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.54 |
| ▸ | ESRRA | P11474 | 1/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | MET | P08581 | 2/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | F7 | P08709 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6564712 | 0.90 | PPIA (0.52) | PPIASGMS2ESRRAMRGPRX4MEN1 | |
| SCHEMBL6566692 | 0.87 | MEN1 (0.61) | PPIASGMS2ESRRAMEN1KMT2A | |
| SCHEMBL6564693 | 0.85 | LRRK2 (0.57) | PPIAESRRAMEN1KMT2AALDH1A1 | |
| SCHEMBL6566043 | 0.85 | LRRK2 (0.56) | PPIASGMS2ESRRAMRGPRX4MEN1 | |
| SCHEMBL6568084 | 0.85 | PPIA (0.60) | PPIASGMS2ESRRAMEN1KMT2A | |
| SCHEMBL6566105 | 0.82 | PPIA (0.58) | PPIAMRGPRX4MEN1KMT2AMAPT | |
| SCHEMBL6566664 | 0.82 | MEN1 (0.57) | PPIASGMS2ESRRAMEN1KMT2A | |
| SCHEMBL6566693 | 0.82 | PARP1 (0.64) | PPIASGMS2MEN1KMT2AALDH1A1 | |
| SCHEMBL6567662 | 0.82 | MEN1 (0.52) | SGMS2ESRRAMEN1KMT2AALDH1A1 | |
| SCHEMBL1646681 | 0.81 | MRGPRX4 (0.60) | PPIASGMS2MRGPRX4ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | PPIA 4339/4885SGMS2 4806/4885ESRRA 706/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.