Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 3/20 | 0.64 |
| ▸ | PPIA | P62937 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566692 | 0.86 | MEN1 (0.61) | PPIAMEN1KMT2ASGMS2ALDH1A1 | |
| SCHEMBL30802658 | 0.86 | PARP1 (0.83) | PARP1PPIAMEN1KMT2ASGMS2 | |
| SCHEMBL29200349 | 0.86 | PARP1 (0.83) | PARP1PPIAMEN1KMT2ASGMS2 | |
| SCHEMBL6564693 | 0.85 | LRRK2 (0.57) | PARP1PPIAMEN1KMT2AALDH1A1 | |
| SCHEMBL6566043 | 0.84 | LRRK2 (0.56) | PARP1PPIAMEN1KMT2ASGMS2 | |
| SCHEMBL6568084 | 0.84 | PPIA (0.60) | PARP1PPIAMEN1KMT2ASGMS2 | |
| SCHEMBL978857 | 0.83 | HTT (0.64) | MEN1KMT2ASGMS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6566105 | 0.82 | PPIA (0.58) | PPIAMEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL6567940 | 0.82 | PPIA (0.58) | PARP1PPIAMEN1KMT2ASGMS2 | |
| SCHEMBL6565756 | 0.81 | MEN1 (0.56) | PPIAMEN1KMT2ASGMS2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2004-12-23 | — | — | US | disclosed |
| EP-1437344-A1 | BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2004-07-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040259912-A1 | Benzine derivatives, process for preparing the same and use thereof | HRH4, HRH2, HRH1 | PARP1 3260/4885PPIA 4339/4885MEN1 4143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.