SCHEMBL6567963

SCHEMBL6567963

NC1CC(C(=O)O)CC1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRR1 P24046 1/20 0.48
ABAT P80404 2/20 0.40
SLC6A12 P48065 3/20 0.37
SLC6A11 P48066 3/20 0.37
SLC6A13 Q9NSD5 3/20 0.37
CYP2C19 P33261 2/20 0.36
CYP1A2 P05177 2/20 0.36
ALOX15 P16050 2/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
PLG P00747 1/20 0.34
PLAT P00750 1/20 0.34
LMNA P02545 1/20 0.34
CYP2D6 P10635 1/20 0.34
SLC1A3 P43003 1/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34
SLC6A4 P31645 1/20 0.34
OAT P04181 1/20 0.34
APLNR P35414 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18581339 1.00 GABRR1 (0.48) GABRR1ABATSLC6A12SLC6A11SLC6A13
SCHEMBL16667748 1.00 GABRR1 (0.48) GABRR1ABATSLC6A12SLC6A11SLC6A13
SCHEMBL31000742 1.00 GABRR1 (0.48) GABRR1ABATSLC6A12SLC6A11SLC6A13
SCHEMBL19506522 0.87 GABRR1 (0.46) GABRR1ABATSLC6A12SLC6A11SLC6A13
SCHEMBL3057992 0.83 CYP2C19 (0.43) GABRR1ABATCYP2C19CYP1A2ALOX15
SCHEMBL3057990 0.83 CYP2C19 (0.43) GABRR1ABATCYP2C19CYP1A2ALOX15
SCHEMBL3489123 0.83 CYP2C19 (0.43) GABRR1ABATCYP2C19CYP1A2ALOX15
SCHEMBL21703887 0.83 CYP2C19 (0.43) GABRR1ABATCYP2C19CYP1A2ALOX15
SCHEMBL3227696 0.83 CYP2C19 (0.43) GABRR1ABATCYP2C19CYP1A2ALOX15
SCHEMBL11938161 0.83 GABRR1 (0.58) GABRR1ABATSLC6A12SLC6A11SLC6A13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017182828-A1 ANTIMICROBIAL AGENTS THE UNIVERSITY OF WARWICK (GB) 2017-10-26 WO disclosed
EP-1210324-B1 SUBSTITUTED CYCLOPENTENES, THEIR PREPARATION AND THEIR USE FOR CHIRAL SCAFFOLDS CHIROTECH TECHNOLOGY LTD (GB) 2004-03-31 EP disclosed
US-6593489-B1 Catalytic stereoselective hydrogenation CHIROTECHTECHNOLOGY LIMITED (GB) 2003-07-15 US disclosed
EP-1210324-A1 SUBSTITUTED CYCLOPENTENES, THEIR PREPARATION AND THEIR USE FOR CHIRAL SCAFFOLDS Chirotech Technology Limited (GB) 2002-06-05 EP disclosed
WO-2001017952-A1 SUBSTITUTED CYCLOPENTENES, THEIR PREPARATION AND THEIR USE FOR CHIRAL SCAFFOLDS CHIROTECH TECHNOLOGY LIMITED (GB) 2001-03-15 WO disclosed