Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 1/20 | 0.46 |
| ▸ | ABAT | P80404 | 2/20 | 0.39 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | FUCA1 | P04066 | 3/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 3/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 3/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
| ▸ | PLAT | P00750 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | OAT | P04181 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18581339 | 0.87 | GABRR1 (0.48) | GABRR1ABATAPLNRSLC6A12SLC6A11 | |
| SCHEMBL16667748 | 0.87 | GABRR1 (0.48) | GABRR1ABATAPLNRSLC6A12SLC6A11 | |
| SCHEMBL31000742 | 0.87 | GABRR1 (0.48) | GABRR1ABATAPLNRSLC6A12SLC6A11 | |
| SCHEMBL6567963 | 0.87 | GABRR1 (0.48) | GABRR1ABATAPLNRSLC6A12SLC6A11 | |
| SCHEMBL14385404 | 0.84 | APLNR (0.43) | GABRR1ABATAPLNRCYP2C19KDM4E | |
| SCHEMBL14389448 | 0.84 | APLNR (0.43) | GABRR1ABATAPLNRCYP2C19KDM4E | |
| SCHEMBL611944 | 0.84 | APLNR (0.43) | GABRR1ABATAPLNRCYP2C19KDM4E | |
| SCHEMBL3489123 | 0.81 | CYP2C19 (0.43) | GABRR1ABATAPLNRCYP2C19KDM4E | |
| SCHEMBL3057990 | 0.81 | CYP2C19 (0.43) | GABRR1ABATAPLNRCYP2C19KDM4E | |
| SCHEMBL21703887 | 0.81 | CYP2C19 (0.43) | GABRR1ABATAPLNRCYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017182828-A1 | ANTIMICROBIAL AGENTS | THE UNIVERSITY OF WARWICK (GB) | 2017-10-26 | — | — | WO | disclosed |