Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL27504536 | 0.89 | — | — | |
| Bromide SCHEMBL1473376 | 0.89 | — | — | |
| Bromide SCHEMBL9003679 | 0.89 | — | — | |
| SCHEMBL5640 | 0.87 | — | — | |
| SCHEMBL10417889 | 0.87 | — | — | |
| SCHEMBL15869348 | 0.87 | — | — | |
| SCHEMBL19876982 | 0.75 | — | — | |
| Ammonia Solution, Strong SCHEMBL4138673 | 0.75 | — | — | |
| SCHEMBL11319151 | 0.75 | — | — | |
| SCHEMBL5859282 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110818679-B | Synthetic method of 4-bromobenzo [ b ] thiophene | 苏州诚和医药化学有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-110818679-A | Synthetic method of 4-bromobenzo [ b ] thiophene | 苏州诚和医药化学有限公司 | 2020-02-21 | — | — | CN | claimed |
| CN-110818679-B | Synthetic method of 4-bromobenzo [ b ] thiophene | 苏州诚和医药化学有限公司 | 2022-04-12 | — | — | CN | disclosed |
| CN-110818679-A | Synthetic method of 4-bromobenzo [ b ] thiophene | 苏州诚和医药化学有限公司 | 2020-02-21 | — | — | CN | disclosed |
| CN-1713787-A | Organic electroluminescent device, method for producing the same, and electronic apparatus | SEIKO EPSON CORP (JP) | 2005-12-28 | — | — | CN | disclosed |
| EP-1478403-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA, INC. (CA) | 2004-11-24 | — | — | EP | disclosed |
| WO-2003063909-A1 | RESPONSIVE MICROGEL AND METHODS RELATED THERETO | SUPRATEK PHARMA INC. (US) | 2003-08-07 | — | — | WO | disclosed |
| WO-1994005292-A1 | GASTROINTESTINAL TREATMENT COMPOSITIONS CONTAINING ALLOPURINOL OR OXYPURINOL AND A SULPHYDRYL GROUP RELEASING AGENT | SALIM AWS SHAKIR MUSTAFA (GB) | 1994-03-17 | — | — | WO | disclosed |
| WO-1994005279-A1 | DERMATOLOGICAL TREATMENT COMPOSITIONS CONTAINING DIMETHYLSULPHONE AND A SULFUR CONTAINING AMINO ACID | SALIM AWS SHAKIR MUSTAFA (GB) | 1994-03-17 | — | — | WO | disclosed |
| US-4945094-A | PROCAINE AND SULFHYDRYL GROUP RELEASING AGENT | SALIM AWS S M (GB) | 1990-07-31 | — | — | US | disclosed |