Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1526045 | 0.89 | — | — | |
| Bromide SCHEMBL6568202 | 0.89 | — | — | |
| Bromide SCHEMBL27504536 | 0.80 | — | — | |
| Bromide SCHEMBL1473376 | 0.80 | — | — | |
| SCHEMBL15869348 | 0.78 | — | — | |
| SCHEMBL10417889 | 0.78 | — | — | |
| SCHEMBL5640 | 0.78 | — | — | |
| Hydrogen Sulfide SCHEMBL5192038 | 0.67 | — | — | |
| Methane SCHEMBL8836373 | 0.67 | — | — | |
| SCHEMBL6731559 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100358888-C | Novel guanidine mimics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2008-01-02 | — | — | CN | disclosed |
| CN-1265675-A | Benzyl compounds which inhibit leukocyte adhesion mediated by VLA-4 | ELAND PHARMACEUTICALS CO (US) | 2000-09-06 | — | — | CN | disclosed |
| CN-1259942-A | Novel guanidine mimics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2000-07-12 | — | — | CN | disclosed |
| CN-1246847-A | Nitrogen containing heteroaromatics as factor Xa inhibitors | DU PONT MERCK PHARMA (US) | 2000-03-08 | — | — | CN | disclosed |
| CN-1039331-C | Depsispeptide derivative, preparation and application of same | FUJISAMA PHARMACEUTICAL CO LTD (JP) | 1998-07-29 | — | — | CN | disclosed |
| EP-0733036-A1 | ALPHA-QUATERNARY-ALPHA-AMINO ACIDS FOR USE AS CNS AGENTS | UNIVERSITY OF BRISTOL (GB) | 1996-09-25 | — | — | EP | disclosed |
| WO-1995015940-A1 | ALPHA-QUATERNARY-ALPHA-AMINO ACIDS FOR USE AS CNS AGENTS | UNIVERSITY OF BRISTOL (GB) | 1995-06-15 | — | — | WO | disclosed |
| CN-1080932-A | Depsipeptide derivative and manufacture method thereof and purposes | FUJISAWA PHARMACEUTICAL CO (JP) | 1994-01-19 | — | — | CN | disclosed |