Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 4/20 | 0.45 |
| ▸ | FDPS | P14324 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL641726 | 0.81 | SMPD1 (0.43) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL4260580 | 0.81 | SMPD1 (0.43) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL3073022 | 0.81 | SMPD1 (0.43) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL641208 | 0.78 | FDPS (0.41) | SMPD1FDPSTSHRTHRBOPRM1 | |
| SCHEMBL3676595 | 0.77 | FDPS (0.45) | SMPD1FDPSSPHK1GGPS1 | |
| SCHEMBL9422192 | 0.77 | FDPS (0.45) | SMPD1FDPSSPHK1GGPS1 | |
| SCHEMBL123833 | 0.77 | FDPS (0.45) | SMPD1FDPSSPHK1GGPS1 | |
| SCHEMBL3677155 | 0.77 | FDPS (0.45) | SMPD1FDPSSPHK1GGPS1 | |
| Hydrochloric Acid SCHEMBL4443834 | 0.76 | FDPS (0.44) | SMPD1FDPSDNM1SPHK1GGPS1 | |
| Hydrochloric Acid SCHEMBL16468331 | 0.76 | FDPS (0.44) | SMPD1FDPSDNM1SPHK1GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1456186-A1 | NOVEL INHIBITOR COMPOUNDS SPECIFIC OF SECRETED NON-PANCREATIC HUMAN A SB 2 /SB PHOSPHOLIPASE OF GROUP II | Yang Ji Chemical Company Ltd. (KR) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003048139-A1 | NOVEL INHIBITOR COMPOUNDS SPECIFIC OF SECRETED NON-PANCREATIC HUMAN A2 PHOSPHOLIPASE OF GROUP II | YANG JI CHEMICAL COMPANY LTD. (KR) | 2003-06-12 | — | — | WO | disclosed |