Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12540146 | 0.75 | BCHE (0.44) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11132326 | 0.75 | KCNH2 (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL6568818 | 0.73 | KCNH2 (0.46) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11135729 | 0.71 | SIGMAR1 (0.49) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL11136447 | 0.70 | SIGMAR1 (0.49) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL196951 | 0.69 | IDO1 (0.67) | IDO1 | |
| SCHEMBL19101896 | 0.69 | TDP1 (0.53) | IDO1 | |
| SCHEMBL18512372 | 0.69 | TDP1 (0.53) | IDO1 | |
| SCHEMBL490540 | 0.69 | KCNH2 (0.68) | KCNH2CHRM2HTR1AADRA2ACHRM1 | |
| SCHEMBL10546787 | 0.69 | BCHE (0.52) | KCNH2CHRM2HTR1AADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |