Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.59 |
| ▸ | DPP4 | P27487 | 17/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 3/20 | 0.49 |
| ▸ | FAP | Q12884 | 2/20 | 0.49 |
| ▸ | PREP | P48147 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568380 | 1.00 | DPP7 (0.59) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL12308338 | 0.79 | DPP7 (0.46) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL15229642 | 0.76 | DPP7 (0.44) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL4449748 | 0.76 | DPP7 (0.50) | DPP7DPP4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9864629 | 0.76 | POLB (0.49) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL4449743 | 0.76 | DPP7 (0.50) | DPP7DPP4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7126229 | 0.74 | DPP7 (0.57) | DPP7DPP4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7117997 | 0.74 | DPP7 (0.57) | DPP7DPP4NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9731595 | 0.74 | POLB (0.48) | DPP7NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL9731600 | 0.74 | POLB (0.48) | DPP7NPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1403277-A1 | Method for synthesis of (2S,3aS,7aS)-1-((S)-alanyl)-octahydro-1H-indole-2-carboxylic acid derivatives and use in the synthesis of perindopril | LES LABORATOIRES SERVIER (FR) | 2004-03-31 | — | — | EP | disclosed |