SCHEMBL6568482

SCHEMBL6568482

CC(C)CON=Cc1cc[c]cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.42
PPARA Q07869 1/20 0.42
MIF P14174 2/20 0.36
GAA P10253 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
ACHE P22303 2/20 0.31
KDM4E B2RXH2 1/20 0.31
S1PR3 Q99500 1/20 0.31
HDAC3 O15379 1/20 0.30
HDAC4 P56524 1/20 0.30
HDAC1 Q13547 1/20 0.30
HDAC7 Q8WUI4 1/20 0.30
HDAC2 Q92769 1/20 0.30
HDAC10 Q969S8 1/20 0.30
HDAC11 Q96DB2 1/20 0.30
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28043070 0.81 PPARG (0.53) PPARGPPARAMIFGAAALDH1A1
SCHEMBL6568997 0.80 PPARG (0.39) PPARGPPARAMIFGAAALDH1A1
SCHEMBL2903032 0.79 SMN1; SMN2 (0.38) MIFGAAALDH1A1SMN1; SMN2NPC1
SCHEMBL2903030 0.79 SMN1; SMN2 (0.38) MIFGAAALDH1A1SMN1; SMN2NPC1
SCHEMBL6077147 0.79 PPARG (0.45) PPARGPPARAMIFSMN1; SMN2NPC1
SCHEMBL6077150 0.79 PPARG (0.45) PPARGPPARAMIFSMN1; SMN2NPC1
SCHEMBL5517442 0.76 PPARG (0.43) PPARGPPARAMIFGAAALDH1A1
SCHEMBL5517437 0.76 PPARG (0.43) PPARGPPARAMIFGAAALDH1A1
SCHEMBL2895178 0.76 PPARG (0.38) PPARGPPARAMIFALDH1A1KDM4E
SCHEMBL2895176 0.76 PPARG (0.38) PPARGPPARAMIFALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP claimed
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP disclosed
US-RE37839-E1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 US disclosed
US-6326399-B1 CONTROLLING INSECTS, ARACHNIDS, NEMATODES BASF AKTIENGESELLSCHAFT (DE) 2001-12-04 US disclosed
US-6316459-B1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AG (DE) 2001-11-13 US disclosed
US-6211190-B1 Pyrimidine derivatives, process and intermediate products for their preparation and pesticides or fungicides containing these derivatives BASF AKTIENGESELLSCHAFT (DE) 2001-04-03 US disclosed
CN-1161687-A Phenylacetic acid alkyl esters BASF AG (DE) 1997-10-08 CN disclosed