Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2895178 | 1.00 | PPARG (0.38) | PPARGPPARAMIFKDM4EALDH1A1 | |
| SCHEMBL5410827 | 0.79 | PPARG (0.49) | PPARGPPARAMIFKDM4EALDH1A1 | |
| SCHEMBL13318830 | 0.79 | PPARG (0.49) | PPARGPPARAMIFKDM4EALDH1A1 | |
| SCHEMBL696767 | 0.78 | PPARG (0.35) | PPARGPPARA | |
| SCHEMBL696768 | 0.78 | PPARG (0.35) | PPARGPPARA | |
| SCHEMBL17233173 | 0.78 | NPC1 (0.52) | PPARGPPARAMIFKDM4EALDH1A1 | |
| SCHEMBL452076 | 0.77 | SRC (0.47) | PPARGPPARAMIFALDH1A1LMNA | |
| SCHEMBL452075 | 0.77 | SRC (0.47) | PPARGPPARAMIFALDH1A1LMNA | |
| SCHEMBL6568482 | 0.76 | PPARG (0.42) | PPARGPPARAMIFKDM4EALDH1A1 | |
| SCHEMBL18590272 | 0.73 | GRIN2D (0.46) | PPARGPPARAALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2640707-B1 | 5-HALOGENOPYRAZOLECARBOXAMIDES | BAYER IP GMBH (DE) | 2017-03-15 | — | — | EP | disclosed |
| EP-2640706-B1 | N-ARYL PYRAZOLE(THIO)CARBOXAMIDES | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| US-20070082877-A1 | Difluoromethylbenzanilides and use thereof for combating micro-organisms, intermediate products and use thereof | BAYER CORPSCIENCE AKTIENGESELLSCHAFT (DE) | 2007-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | PPARG 2001/4885PPARA 2126/4885MIF 4857/4885 |
| US-20070082877-A1 | Difluoromethylbenzanilides and use thereof for combating micro-organisms, intermediate products and use thereof | FBL, Q6ZSR9, DDT | PPARG 2497/4885PPARA 2960/4885MIF 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.