Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 14/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6757602 | 1.00 | HTR6 (0.37) | HTR6CYP24A1KDM4EUBE2NRAPGEF4 | |
| SCHEMBL6568535 | 1.00 | HTR6 (0.37) | HTR6CYP24A1KDM4EUBE2NRAPGEF4 | |
| SCHEMBL6757596 | 1.00 | HTR6 (0.37) | HTR6CYP24A1KDM4EUBE2NRAPGEF4 | |
| SCHEMBL6757600 | 1.00 | HTR6 (0.37) | HTR6CYP24A1KDM4EUBE2NRAPGEF4 | |
| SCHEMBL6570213 | 0.79 | SMN1; SMN2 (0.33) | CYP24A1MEN1KMT2A | |
| SCHEMBL6570206 | 0.79 | SMN1; SMN2 (0.33) | CYP24A1MEN1KMT2A | |
| SCHEMBL4622561 | 0.74 | DHODH (0.34) | — | |
| SCHEMBL4622563 | 0.74 | DHODH (0.34) | — | |
| SCHEMBL4622571 | 0.74 | DHODH (0.34) | — | |
| SCHEMBL4622568 | 0.74 | DHODH (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432694-A1 | STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF 2-YL CHROMAN DERIVATIVES | Wyeth (US) | 2004-06-30 | — | — | EP | disclosed |
| WO-2003031428-A1 | STEREOSPECIFIC PROCESS FOR THE SYNTHESIS OF 2-YL CHROMAN DERIVATIVES | WYETH (US) | 2003-04-17 | — | — | WO | disclosed |