Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.67 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4266873 | 0.81 | RAB9A (1.00) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL812273 | 0.81 | RAB9A (1.00) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL2752734 | 0.79 | RAB9A (0.96) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL6567236 | 0.77 | CNR1 (0.62) | SMN1; SMN2EPHX2NPSR1 | |
| SCHEMBL6523292 | 0.77 | RAB9A (0.49) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL6724549 | 0.76 | RAB9A (0.80) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL28218814 | 0.76 | EPHX1 (0.90) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL13756244 | 0.76 | EPHX1 (0.86) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL4347065 | 0.76 | RAB9A (0.66) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 | |
| SCHEMBL4345564 | 0.76 | RAB9A (0.63) | RAB9AEPHX1SMN1; SMN2EPHX2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |