Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566923 | 0.82 | IDO1 (0.52) | GAAMAPTHTTLMNAPOLB | |
| SCHEMBL4354700 | 0.82 | CXCR1 (0.48) | GAAMAPTHTTLMNAPOLB | |
| SCHEMBL14850288 | 0.82 | GAA (0.71) | GAAMAPTHTTLMNAPOLB | |
| SCHEMBL6566862 | 0.81 | CXCR2 (0.54) | GAAMAPTHTTLMNAPOLB | |
| SCHEMBL4355807 | 0.80 | KMT2A (0.54) | GAAMAPTHTTLMNAPOLB | |
| SCHEMBL4359261 | 0.80 | KMT2A (0.54) | MAPTHTTLMNAPOLBKMT2A | |
| SCHEMBL4342367 | 0.80 | HTT (0.47) | GAAMAPTHTTLMNAPOLB | |
| SCHEMBL10597378 | 0.79 | SMN1; SMN2 (0.62) | GAAMAPTHTTPOLBKMT2A | |
| SCHEMBL9400389 | 0.75 | NPC1 (0.66) | GAAMAPTHTTLMNAPOLB | |
| SCHEMBL6565420 | 0.75 | MEN1 (0.51) | MAPTHTTLMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |