Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.52 |
| ▸ | EP300 | Q09472 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.44 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568506 | 0.84 | IDO1 (0.60) | IDO1EP300HSP90AA1MAPTHTT | |
| SCHEMBL6568668 | 0.82 | GAA (0.61) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL4354700 | 0.77 | CXCR1 (0.48) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL6566862 | 0.76 | CXCR2 (0.54) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL4355807 | 0.75 | KMT2A (0.54) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL20306580 | 0.74 | IDO1 (0.59) | IDO1EP300HSP90AA1PSDKAT2B | |
| SCHEMBL10597378 | 0.74 | SMN1; SMN2 (0.62) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL10447368 | 0.72 | EP300 (0.55) | IDO1EP300HSP90AA1POLBPSD | |
| SCHEMBL4358325 | 0.72 | POLB (0.60) | POLBMAPTHTTMEN1KMT2A | |
| SCHEMBL4344564 | 0.72 | HTT (0.53) | POLBMAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1402887-A1 | New compounds for the inhibition of undesired cell proliferation and use thereof | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |
| EP-1402888-A1 | The use of substituted carbocyclic compounds as rotamases inhibitors | Jerini AG (DE) | 2004-03-31 | — | — | EP | claimed |