SCHEMBL6568685

SCHEMBL6568685

COc1c(CCCCO)cc(C)cc1C(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 1/20 0.42
CYP2C9 P11712 2/20 0.41
CYP2C19 P33261 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
HIF1A Q16665 2/20 0.41
CYP2D6 P10635 2/20 0.38
ALDH1A1 P00352 2/20 0.38
CA2 P00918 1/20 0.38
POLB P06746 1/20 0.38
TYR P14679 1/20 0.38
HSD17B10 Q99714 1/20 0.38
CYP3A4 P08684 2/20 0.35
VCAM1 P19320 2/20 0.35
ALOX5 P09917 2/20 0.33
TSHR P16473 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6567754 0.95 HSPA5 (0.44) HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL7942450 0.88 TNKS2 (0.37) HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL6568810 0.85 RARG (0.36) CYP2C19ALDH1A1CA2CYP3A4VCAM1
SCHEMBL6567747 0.81 HSPA5 (0.41) HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL7943136 0.81 VCAM1 (0.37) HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL6567748 0.80 RARG (0.36) CYP2C19ALDH1A1CA2CYP3A4VCAM1
SCHEMBL6567368 0.80 HSPA5 (0.64) HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL6568862 0.78 HSPA5 (0.62) HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL6568748 0.78 HSPA5 (0.62) HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A
SCHEMBL7792834 0.78 NPSR1 (0.45) HSPA5CYP2C9CYP2C19SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1484334-A2 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-12-08 EP disclosed
US-20040225145-A1 Process for producing phosphite SUMITOMO CHEMICAL COMPANY, LIMITED 2004-11-11 US disclosed
EP-0823435-B1 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL CO (JP) 2001-11-21 EP disclosed
US-6242514-B1 CYCLIC PHOSPHATE OR PHOSPHONATE; HEAT AND OXIDATION STABILIZER ESPECIALLY FOR OLEFIN POLYMERS AND ENGINEERING THERMOPLASTICS SUMITOMO CHEMICAL COMPANY, LTD. (JP) 2001-06-05 US disclosed
US-5914361-A IMPART HEAT STABILITY TO ORGANIC MATERIALS, INCLUDING POLYOLEFINS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-06-22 US disclosed
US-5889095-A OXYGEN AND HEAT RESISTANCE SUMITOMO CHEMICAL COMPANY, LTD. (JP) 1999-03-30 US disclosed
EP-0823435-A2 Phosphites, process for producing the same and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-02-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040225145-A1 Process for producing phosphite PHOSPHO1, PLCG1, PLCG2 HSPA5 4485/4885CYP2C9 1692/4885CYP2C19 1924/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.