Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.41 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.41 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | TNKS | O95271 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3954647 | 0.81 | PTGER3 (0.49) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL16048819 | 0.79 | CA1 (0.53) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL16048816 | 0.79 | CA1 (0.53) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL8296729 | 0.79 | CA1 (0.44) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL8296698 | 0.78 | MIF (0.54) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL6817329 | 0.76 | ITGB2 (0.52) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL6568833 | 0.76 | ITGB2 (0.52) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL6503055 | 0.74 | CA1 (0.40) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL6240290 | 0.74 | ITGB2 (0.43) | CA1CA2CA4NFKB1MIF | |
| SCHEMBL6502267 | 0.74 | CA1 (0.40) | CA1CA2CA4NFKB1MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |