Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 8/20 | 0.52 |
| ▸ | ICAM1 | P05362 | 8/20 | 0.52 |
| ▸ | ITGAL | P20701 | 8/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6568833 | 1.00 | ITGB2 (0.52) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6312254 | 0.88 | ITGB2 (0.53) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6312964 | 0.87 | ITGB2 (0.52) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6240293 | 0.86 | ITGB2 (0.43) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6240290 | 0.86 | ITGB2 (0.43) | ITGB2ICAM1ITGALCA1CA2 | |
| SCHEMBL6238628 | 0.85 | PLA2G4A (0.43) | ITGB2ICAM1ITGALMIFHDAC1 | |
| SCHEMBL6238622 | 0.85 | PLA2G4A (0.43) | ITGB2ICAM1ITGALMIFHDAC1 | |
| SCHEMBL4278719 | 0.84 | ITGAL (0.67) | ITGB2ICAM1ITGALHTTMAPT | |
| SCHEMBL4278725 | 0.84 | ITGAL (0.67) | ITGB2ICAM1ITGALHTTMAPT | |
| SCHEMBL6316878 | 0.81 | ITGB2 (0.43) | ITGB2ICAM1ITGALPTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165505-B1 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LAB (US) | 2004-09-08 | — | — | EP | disclosed |