Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL4435975 | 0.95 | CNR1 (0.41) | ATMACACBCNR1RAB9ACHRNA4 | |
| SCHEMBL892942 | 0.88 | ATM (0.40) | ATMACACBRAB9ACHRNA4SMN1; SMN2 | |
| SCHEMBL19064377 | 0.86 | RAB9A (0.54) | ATMACACBRAB9ASMN1; SMN2NPC1 | |
| SCHEMBL893060 | 0.83 | CHRNA4 (0.41) | ATMACACBCHRNA4SMN1; SMN2GAA | |
| SCHEMBL892675 | 0.82 | ACACB (0.44) | ATMACACBRAB9ACHRNA4SMN1; SMN2 | |
| SCHEMBL893320 | 0.82 | ACACB (0.39) | ATMACACBRAB9ACHRNA4SMN1; SMN2 | |
| SCHEMBL3940897 | 0.81 | CHRNA4 (0.40) | ATMACACBCHRNA4SMN1; SMN2GAA | |
| SCHEMBL17883351 | 0.81 | RAB9A (0.55) | ACACBRAB9ASMN1; SMN2NPC1GAA | |
| SCHEMBL26750156 | 0.81 | ADORA2A (0.40) | ATMACACBCHRNA4ALDH1A1AR | |
| Hydrochloric Acid SCHEMBL3938535 | 0.80 | CHRNA4 (0.39) | ATMACACBCHRNA4SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115160250-B | 4, 6-Biphenol derivative and application thereof | 沈阳药科大学 | 2024-06-04 | — | — | CN | claimed |
| CN-115160250-A | 4, 6-biphenyldiphenol derivatives and their use | 沈阳药科大学 | 2022-10-11 | — | — | CN | claimed |
| CN-115160250-B | 4, 6-Biphenol derivative and application thereof | 沈阳药科大学 | 2024-06-04 | — | — | CN | disclosed |
| CN-115160250-A | 4, 6-biphenyldiphenol derivatives and their use | 沈阳药科大学 | 2022-10-11 | — | — | CN | disclosed |
| WO-2022056447-A1 | CARBOXYLIC ACID-CONTAINING COMPOUNDS AS MODULATORS OF BIS-PHOSPHOGLYCERATE MUTASE FOR THE TREATMENT OF SICKLE CELL DISEASE | GENZYME CORPORATION (US) | 2022-03-17 | — | — | WO | disclosed |
| CN-107540624-A | Heat shock protein inhibitors and its preparation method and application | 广州市恒诺康医药科技有限公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-107108591-A | It is used as the resorcinol analog derivative of HSP90 inhibitor | 正大天晴药业集团股份有限公司 | 2017-08-29 | — | — | CN | disclosed |
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2012-02-23 | — | — | US | disclosed |
| EP-2370076-A2 | PHARMACEUTICAL COMBINATION COMPRISING A HSP 90 INHIBITOR AND A MTOR INHIBITOR | Novartis AG (CH) | 2011-10-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046266-A1 | RESORCINOL DERIVATIVES AS HSP90 INHIBITORS | HSP90AB1, HSP90AA1, HSP90AB2P | ATM 2501/4885ACACB 1934/4885CNR1 4593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.