Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 5/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 9/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 2/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570293 | 0.84 | POLB (0.48) | S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL6569386 | 0.82 | EPHX2 (0.50) | CETP | |
| SCHEMBL6570358 | 0.82 | EPHX2 (0.50) | CETP | |
| SCHEMBL6569306 | 0.82 | EPHX2 (0.50) | CETP | |
| SCHEMBL6569347 | 0.82 | EPHX2 (0.50) | CETP | |
| SCHEMBL6569223 | 0.82 | EPHX2 (0.50) | CETP | |
| SCHEMBL6568523 | 0.81 | CETP (0.48) | CETP | |
| SCHEMBL6568704 | 0.81 | EPHX2 (0.48) | CETP | |
| SCHEMBL6569503 | 0.80 | HPGD (0.50) | CETP | |
| SCHEMBL6570330 | 0.79 | TDP1 (0.46) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1156054-B1 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO (JP) | 2004-04-14 | — | — | EP | claimed |
| US-6495533-B1 | TUMOR NECROSIS FACTOR INHIBITORS; RHEUMATOID ARTHRITIS, ULCERATIVE COLITIS, CROHN'S DISEASE, HEPATITIS, SEPSIS, HEMORRHAGIC SHOCK, MULTIPLE SCLEROSIS, CEREBRAL INFARCTION, DIABETES, INTERSTITIAL PNEUMONIA, PAIN, HIV | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-12-17 | — | — | US | claimed |
| EP-1156054-A1 | DRUGS CONTAINING PHOSPHORIC ACID DERIVATIVES AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-11-21 | — | — | EP | claimed |