SCHEMBL6569684

SCHEMBL6569684

C=C(C)C(=O)OCCC[Si](OC)(OC)OC.C=C(C)C(=O)OCCN(C)C.C=C(C)C(=O)OCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 2/20 0.40
ALDH1A1 P00352 5/20 0.39
TDP1 Q9NUW8 2/20 0.38
HTT P42858 2/20 0.38
POLB P06746 1/20 0.38
APEX1 P27695 1/20 0.38
TSHR P16473 3/20 0.37
CYP3A4 P08684 1/20 0.37
MAPK1 P28482 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
LMNA P02545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GAA P10253 1/20 0.36
CHRM2 P08172 1/20 0.36
CHRM4 P08173 1/20 0.36
CHRM5 P08912 1/20 0.36
CHRM3 P20309 1/20 0.36
MAPT P10636 1/20 0.35
HPGD P15428 1/20 0.35
EGFR P00533 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6037217 0.87 ALDH1A1 (0.50) CHRM1ALDH1A1TDP1HTTPOLB
SCHEMBL28122034 0.86 TSHR (0.45) CHRM1ALDH1A1TDP1HTTPOLB
SCHEMBL6570450 0.81 ALDH1A1 (0.35) ALDH1A1TDP1HTTPOLBAPEX1
Toluene SCHEMBL27784195 0.80 TDP1 (0.45) ALDH1A1TDP1HTTPOLBAPEX1
O-Xylene SCHEMBL28563702 0.79 TSHR (0.43) ALDH1A1TDP1HTTPOLBAPEX1
SCHEMBL26969552 0.78 TSHR (0.40) CHRM1ALDH1A1TDP1HTTPOLB
Styrene SCHEMBL10627023 0.77 TDP1 (0.42) ALDH1A1TDP1HTTPOLBAPEX1
SCHEMBL15276 0.77 TSHR (0.55) ALDH1A1TDP1HTTPOLBAPEX1
SCHEMBL5446210 0.77 TSHR (0.55) ALDH1A1TDP1HTTPOLBAPEX1
(Chloromethyl)Benzene SCHEMBL128111 0.76 CHRM1 (0.49) CHRM1ALDH1A1TDP1HTTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0999243-B1 Alkoxysilane binders as additives in ink jet inks DU PONT (US) 2004-04-21 EP disclosed
US-6180690-B1 AQUEOUS INK JET INK COMPRISING AN AQUEOUS VEHICLE, A COLORANT, AND AN ALKOXYSILANE BINDER ADDITIVE, A BLOCK COPOLYMER PIGMENT DISPERSANT, EXCELLENT WATER AND SMEARFASTNESS AND PRINT QUALITY E. I. DU PONT DE NEMOURS AND COMPANY 2001-01-30 US disclosed
EP-0999243-A1 Alkoxysilane binders as additives in ink jet inks E.I. DU PONT DE NEMOURS AND COMPANY (US) 2000-05-10 EP disclosed