Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 16/20 | 0.73 |
| ▸ | ITGB2 | P05107 | 14/20 | 0.73 |
| ▸ | ICAM1 | P05362 | 14/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6317727 | 1.00 | ITGAL (0.73) | ITGALITGB2ICAM1RAB9AKDM4E | |
| SCHEMBL7641657 | 0.90 | ITGAL (0.76) | ITGALITGB2ICAM1RAB9AKDM4E | |
| SCHEMBL6920036 | 0.90 | ITGAL (0.76) | ITGALITGB2ICAM1RAB9AKDM4E | |
| SCHEMBL6493194 | 0.87 | ITGAL (0.73) | ITGALITGB2ICAM1RAB9AKDM4E | |
| SCHEMBL6493588 | 0.87 | ITGAL (0.73) | ITGALITGB2ICAM1RAB9AKDM4E | |
| SCHEMBL6568431 | 0.84 | ITGAL (0.68) | ITGALITGB2ICAM1 | |
| SCHEMBL6310695 | 0.84 | ITGAL (0.68) | ITGALITGB2ICAM1 | |
| SCHEMBL5196362 | 0.82 | ITGB2 (0.72) | ITGALITGB2ICAM1 | |
| SCHEMBL7645229 | 0.79 | ITGAL (0.62) | ITGALITGB2ICAM1 | |
| SCHEMBL6567852 | 0.78 | ITGAL (0.61) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481968-A2 | Cell adhesion-inhibiting anti-inflammatory and immune-suppressive compounds | Abbott Laboratories (US) | 2004-12-01 | — | — | EP | disclosed |