Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.35 |
| ▸ | RORA | P35398 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RORB | Q92753 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1637358 | 0.98 | APP (0.40) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL7021752 | 0.96 | APP (0.37) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL6572228 | 0.94 | APP (0.38) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL7032017 | 0.94 | APP (0.40) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL17736383 | 0.91 | APP (0.40) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL12704960 | 0.91 | APP (0.40) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL9912971 | 0.91 | APP (0.41) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL12249799 | 0.91 | APP (0.41) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL9912891 | 0.91 | APP (0.41) | APPMAPTPOLBKDM4EL3MBTL1 | |
| SCHEMBL15025927 | 0.91 | POLB (0.43) | APPMAPTPOLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908787-B1 | Indolocarbazole Photoconductors | XEROX CORP (US) | 2004-04-14 | — | — | EP | claimed |
| EP-0908787-A2 | Indolocarbazole Photoconductors | Xerox Corporation (US) | 1999-04-14 | — | — | EP | claimed |