SCHEMBL65699

SCHEMBL65699

Nc1cccc2cccc(N)c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
JAK2 O60674 1/20 0.54
RPS6KA3 P51812 1/20 0.54
MELK Q14680 1/20 0.54
STK24 Q9Y6E0 1/20 0.54
ALDH1A1 P00352 9/20 0.53
CYP3A4 P08684 8/20 0.53
TSHR P16473 6/20 0.53
HSD17B10 Q99714 6/20 0.53
HPGD P15428 5/20 0.53
CYP1A2 P05177 3/20 0.53
CYP1A1 P04798 1/20 0.53
CYP1B1 Q16678 1/20 0.53
KEAP1 Q14145 1/20 0.52
TDP1 Q9NUW8 1/20 0.47
CASP1 P29466 2/20 0.47
ALOX15 P16050 2/20 0.47
CASP7 P55210 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
PIK3CA P42336 1/20 0.45
TYMS P04818 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29349435 1.00 JAK2 (0.54) JAK2RPS6KA3MELKSTK24ALDH1A1
Fluoride SCHEMBL11274176 0.97 JAK2 (0.52) JAK2RPS6KA3MELKSTK24ALDH1A1
SCHEMBL28313238 0.97 JAK2 (0.52) JAK2RPS6KA3MELKSTK24ALDH1A1
SCHEMBL28296931 0.97 JAK2 (0.52) JAK2RPS6KA3MELKSTK24ALDH1A1
Hydrochloric Acid SCHEMBL11277860 0.97 JAK2 (0.52) JAK2RPS6KA3MELKSTK24ALDH1A1
SCHEMBL28276823 0.97 JAK2 (0.52) JAK2RPS6KA3MELKSTK24ALDH1A1
SCHEMBL9627127 0.97 JAK2 (0.52) JAK2RPS6KA3MELKSTK24ALDH1A1
Hydrochloric Acid SCHEMBL11698588 0.97 JAK2 (0.52) JAK2RPS6KA3MELKSTK24ALDH1A1
Ammonia Solution, Strong SCHEMBL2638226 0.97 JAK2 (0.52) JAK2RPS6KA3MELKSTK24ALDH1A1
SCHEMBL14742902 0.90 ALDH1A1 (0.59) JAK2RPS6KA3MELKSTK24ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5620 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025237878-A1 LOW BLEEDING PERYLENE BLACK PIGMENTS AND PROCESS FOR PRODUCING THE SAME SUN CHEMICAL B.V. (NL) 2025-11-20 WO claimed
US-20250057867-A1 NUCLEOSIDE PHOSPHORAMIDATES GILEAD SCIENCES INC (US) 2025-02-20 US claimed
EP-3980769-B1 METHOD AND SENSOR FOR DETECTION OF TRIACETONE TRIPEROXIDE (TATP), DIACETONE DIPEROXIDE (DADP), HEXAMETHYLENE TRIPEROXIDE DIAMINE (HMTD) AND HYDROGEN PEROXIDE BUNDESREPUBLIK DEUTSCHLAND VERTRETEN DURCH DEN BUNDESMINISTER FUER WIRTSCH UND ENERGIE DIESER VERTRE (DE) 2025-01-22 EP claimed
WO-2024154978-A1 AMPHIPATHIC POLYAMIDE-BASED REVERSE OSMOSIS SEPARATION MEMBRANE WITH IMPROVED FOULING RESISTANCE AND WEAR RESISTANCE AND MANUFACTURING METHOD THEREFOR 도레이첨단소재 주식회사 2024-07-25 WO claimed
CN-116285974-B Preparation method of carbon-based quantum dot with high quantum yield and light stability 中国科学院上海微系统与信息技术研究所 2024-07-19 CN claimed
CN-118344839-A High-initial-adhesion UV light/moisture dual-curing polyurethane hot melt adhesive and preparation method thereof 北京华腾新材料股份有限公司 2024-07-16 CN claimed
CN-118320793-A Functionalized magnetic nanocomposite MWCNTs/Fe3O4Preparation method of @ PDAN 浙江工业大学 2024-07-12 CN claimed
CN-118324787-A Functional probe capable of dual-mode excitation and dual-channel distinction of oxidative stress and preparation 陕西科技大学 2024-07-12 CN claimed
CN-118307539-A Production method of solvent red 179 安徽清科瑞洁新材料有限公司 2024-07-09 CN claimed
CN-118307529-A 2, 3-Dihydronaphthalene-embedded m-diazabenzene compound, synthesis method, pharmaceutical composition and application thereof 中国科学院上海药物研究所 2024-07-09 CN claimed
US-4312934-A REACTIONOF AROMATIC AMINE OR HYDROXYLAMINE WITH POLYMER CONTAINING NITRATE GROUPS BARD LABORATORIES, INC. (US) 1982-01-26 US claimed
US-4172937-A REACTION OF A DIALDEHYDE AND DIAMINE IN A PHENOLIC COMPOUND ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-10-30 US claimed
EP-0002906-A2 Novel perimidines, their preparation, formulations and use as immunosuppressives ELI LILLY AND COMPANY (US) 1979-07-11 EP claimed
US-4128569-A FROM AN AMINE AND PHOSGENE BASF AKTIENGESELLSCHAFT (DE) 1978-12-05 US claimed
US-4107151-A FROM POLYISOCYANATE, CHAIN POLYOL, AROMATIC DIAMINE, POLYOL OR AMINO ALCOHOL WITH URETHANE BOND IHARA CHEMICAL COMPANY CO., LTD. (JP) 1978-08-15 US claimed
US-4049457-A WITH AN ORGANIC ACID BARD LABORATORIES, INC. (US) 1977-09-20 US claimed
US-4029637-A FIBERS AKZONA INCORPORATED (US) 1977-06-14 US claimed
US-4028102-A WITH 4,10-BENZOTHIOXANTHENE-3,1'-DICARBOXYLIC ACID ANHYDRIDE HOECHST AKTIENGESELLSCHAFT (DT) 1977-06-07 US claimed
US-3972717-A DYE, PHOTOCONDUCTOR HOECHST AKTIENGESELLSCHAFT (DT) 1976-08-03 US claimed
US-3966703-A Asymmetrical frisazo dyestuffs derived from diazotized 2,7-diamino-carbazole BAYER AKTIENGESELLSCHAFT (DT) 1976-06-29 US claimed