Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.31 |
| ▸ | TDO2 | P48775 | 2/20 | 0.31 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10245468 | 0.79 | AOC3 (0.35) | HTTAOC3IDO1TDO2TRPA1 | |
| SCHEMBL11664812 | 0.74 | AOC3 (0.36) | HSD11B1HTTAOC3SLC6A4SLC6A3 | |
| SCHEMBL18022529 | 0.73 | AOC3 (0.39) | HTTAOC3IDO1TDO2TRPA1 | |
| SCHEMBL1754096 | 0.73 | AOC3 (0.39) | HTTAOC3IDO1TDO2TRPA1 | |
| SCHEMBL20224127 | 0.73 | AOC3 (0.39) | HTTAOC3IDO1TDO2TRPA1 | |
| SCHEMBL16847361 | 0.70 | HSD11B1 (0.38) | HSD11B1HTTAOC3IDO1TDO2 | |
| SCHEMBL17086713 | 0.70 | HSD11B1 (0.38) | HSD11B1HTTAOC3IDO1TDO2 | |
| SCHEMBL8053971 | 0.70 | HSD11B1 (0.38) | HSD11B1HTTAOC3IDO1TDO2 | |
| SCHEMBL13852045 | 0.69 | IDO1 (0.39) | HTTAOC3IDO1TDO2TRPA1 | |
| SCHEMBL10194742 | 0.69 | IDO1 (0.39) | HTTAOC3IDO1TDO2TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404325-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096420-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |