Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11179141 | 0.82 | HRH3 (0.52) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL5489927 | 0.82 | HRH3 (0.52) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL10846103 | 0.80 | HRH3 (0.48) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL24277911 | 0.78 | HRH3 (0.48) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL10032106 | 0.78 | HRH3 (0.48) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL820814 | 0.78 | HRH3 (0.48) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL27879440 | 0.77 | HRH3 (0.42) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL179355 | 0.75 | CARM1 (0.44) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL15658696 | 0.74 | HRH3 (0.44) | HRH3CARM1PRMT6PRMT8SIGMAR1 | |
| SCHEMBL11889486 | 0.74 | HRH3 (0.56) | HRH3SIGMAR1CYP1A2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |