Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570349 | 0.98 | MC4R (0.49) | MC4RSIGMAR1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5487608 | 0.83 | HRH3 (0.46) | MC4RSIGMAR1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5713520 | 0.81 | HRH3 (0.52) | MC4RSIGMAR1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL5713485 | 0.80 | HRH3 (0.55) | MC4RSIGMAR1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL28839912 | 0.78 | CYP1A2 (0.57) | MC4RSIGMAR1SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL11828025 | 0.75 | SIGMAR1 (0.50) | MC4RSIGMAR1SLC6A3LTA4HCYP1A2 | |
| Hydrochloric Acid SCHEMBL8512322 | 0.74 | SIGMAR1 (0.49) | MC4RSIGMAR1SLC6A3LTA4HCYP1A2 | |
| SCHEMBL29006725 | 0.73 | SIGMAR1 (0.45) | MC4RSIGMAR1SLC6A3LTA4HCYP1A2 | |
| SCHEMBL9791933 | 0.71 | SIGMAR1 (0.50) | SIGMAR1SLC6A3SLC6A2SLC6A4CYP1A2 | |
| SCHEMBL4896743 | 0.70 | CYP1A2 (0.51) | MC4RSLC6A3SLC6A2SLC6A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100503-B1 | NON-IMIDAZOLE ALKYLAMINES AS HISTAMINE H 3?-RECEPTOR LIGANDS AND THEIR THERAPEUTIC APPLICATIONS | ILE BIOPROJET SOC CIV (FR) | 2004-09-22 | — | — | EP | claimed |