SCHEMBL6570458

SCHEMBL6570458

COC=C(C(=O)OC)c1ccccc1CON1C(=O)c2ccccc2C1=O

nearest known ligand 0.55

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.45
HTT P42858 1/20 0.45
GAA P10253 2/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
MAPT P10636 1/20 0.39
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8023050 1.00 ALDH1A1 (0.45) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL7623126 0.89 ALDH1A1 (0.46) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL8611140 0.89 ALDH1A1 (0.46) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL11001273 0.81 ALDH1A1 (0.52) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL20823476 0.79 HIF1A (0.33) ALDH1A1GAA
SCHEMBL30477008 0.79 HIF1A (0.56) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL7623643 0.79 HIF1A (0.56) ALDH1A1HTTGAAKMT2AMEN1
SCHEMBL8403431 0.78 IDO1 (0.41) ALDH1A1
SCHEMBL9184121 0.78 IDO1 (0.41) ALDH1A1
SCHEMBL6571734 0.78 IDO1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0463488-B2 O-Benzyl oxime ethers and fungicides containing them BASF AG (DE) 2004-04-21 EP disclosed
US-RE37839-E1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 2002-09-10 US disclosed
US-6326399-B1 CONTROLLING INSECTS, ARACHNIDS, NEMATODES BASF AKTIENGESELLSCHAFT (DE) 2001-12-04 US disclosed
US-6316459-B1 O-benzyloxime ethers and crop protection agents containing these compounds BASF AG (DE) 2001-11-13 US disclosed
EP-0918748-B1 FUNGICIDES ZENECA LTD (GB) 2000-12-20 EP disclosed
US-6124356-A Fungicides ZENECA LIMITED (GB) 2000-09-26 US disclosed
US-5935999-A Aralkyoxy alkoximino derivatives and their use as fungicides ZENECA LIMITED (GB) 1999-08-10 US disclosed
EP-0918748-A1 FUNGICIDES ZENECA LIMITED (GB) 1999-06-02 EP disclosed
EP-0669319-B1 O-Benzyloxime ethers and plant-protecting agents containing them BASF AG (DE) 1998-09-02 EP disclosed
WO-1998004520-A1 FUNGICIDES ZENECA LIMITED (GB) 1998-02-05 WO disclosed
US-5563168-A FUNGICIDES, INSECTICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-10-08 US disclosed
EP-0675876-A1 ARALKYLOXY- AND ARALKYLTHIO ALKOXIMINO DERIVATIVES AND THEIR USE AS FUNGICIDES. ZENECA LTD (GB) 1995-10-11 EP disclosed
EP-0669319-A2 O-Benzyloxime ethers and plant-protecting agents containing them BASF AKTIENGESELLSCHAFT (DE) 1995-08-30 EP disclosed
EP-0664795-A1 PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES ZENECA LIMITED (GB) 1995-08-02 EP disclosed
US-5387607-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1995-02-07 US disclosed
WO-1994014761-A1 ARALKYLOXY- AND ARALKYLTHIO ALKOXIMINO DERIVATIVES AND THEIR USE AS FUNGICIDES ZENECA LIMITED (GB) 1994-07-07 WO disclosed
WO-1994008968-A1 PROPENOIC ACID DERIVATIVES USEFUL AS FUNGICIDES ZENECA LIMITED (GB) 1994-04-28 WO disclosed
US-5292759-A O-benzyloxime ethers and crop protection agents containing these compounds BASF AKTIENGESELLSCHAFT (DE) 1994-03-08 US disclosed
US-5194662-A Insecticides, fungicides for plants BASF AKTIENGESELLSCHAFT (DE) 1993-03-16 US disclosed
EP-0463488-A1 O-Benzyl oxime ethers and fungicides containing them BASF Aktiengesellschaft (DE) 1992-01-02 EP disclosed