Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.42 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570598 | 0.90 | MIF (0.53) | MEN1KMT2ACHRM3L3MBTL1SMN1; SMN2 | |
| SCHEMBL4504278 | 0.81 | CETP (0.49) | MEN1KMT2ACHRM3L3MBTL1SMN1; SMN2 | |
| SCHEMBL4619588 | 0.80 | CYP2C19 (0.59) | KMT2ACHRM3SMN1; SMN2CYP2D6CYP2C19 | |
| SCHEMBL6570728 | 0.79 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2BLMCYP2D6CYP2C19 | |
| SCHEMBL5929556 | 0.79 | L3MBTL1 (0.52) | L3MBTL1SMN1; SMN2BLMCYP2D6CYP2C19 | |
| SCHEMBL2066034 | 0.79 | MEN1 (0.55) | MEN1KMT2ACHRM3L3MBTL1SMN1; SMN2 | |
| SCHEMBL14430429 | 0.77 | CHRM3 (0.50) | MEN1KMT2ACHRM3L3MBTL1SMN1; SMN2 | |
| SCHEMBL30601200 | 0.76 | MEN1 (0.49) | MEN1KMT2ACHRM3L3MBTL1SMN1; SMN2 | |
| SCHEMBL4872782 | 0.76 | L3MBTL1 (0.47) | KMT2AL3MBTL1SMN1; SMN2BLMCYP2D6 | |
| SCHEMBL745452 | 0.76 | CYP2C19 (0.56) | L3MBTL1SMN1; SMN2BLMCYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629472-B2 | Method for producing optically active compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-12-08 | — | — | US | disclosed |
| US-20070276143-A1 | Method for producing optically active compound | YAMANO TORU | 2007-11-29 | — | — | US | disclosed |
| US-7247732-B2 | Method for producing optically active compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-07-24 | — | — | US | disclosed |
| EP-1489070-A1 | PROCESS FOR PRODUCTION OF OPTICALLY ACTIVE COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276143-A1 | Method for producing optically active compound | CYP8B1, HRH3, HRH1 | MEN1 235/4885KMT2A 1469/4885CHRM3 336/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.