Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 3/20 | 0.52 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.52 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.52 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.52 |
| ▸ | ADK | P55263 | 4/20 | 0.52 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885324 | 0.86 | ADK (0.62) | SLC29A1SLC28A1SLC28A2SLC28A3ADK | |
| SCHEMBL2143266 | 0.86 | ADK (0.62) | SLC29A1SLC28A1SLC28A2SLC28A3ADK | |
| SCHEMBL2143269 | 0.86 | ADK (0.62) | SLC29A1SLC28A1SLC28A2SLC28A3ADK | |
| Immunicillin H SCHEMBL31416024 | 0.75 | ADK (0.65) | SLC29A1ADK | |
| Tubercidin SCHEMBL23982115 | 0.74 | ADK (0.82) | SLC29A1SLC28A1SLC28A2SLC28A3ADK | |
| SCHEMBL13005628 | 0.74 | ADK (0.64) | SLC29A1ADK | |
| Tubercidin SCHEMBL23982350 | 0.74 | ADK (0.82) | SLC29A1SLC28A1SLC28A2SLC28A3ADK | |
| Tubercidin SCHEMBL20938187 | 0.74 | ADK (0.82) | SLC29A1SLC28A1SLC28A2SLC28A3ADK | |
| Tubercidin SCHEMBL20418952 | 0.74 | ADK (0.82) | SLC29A1SLC28A1SLC28A2SLC28A3ADK | |
| Tubercidin SCHEMBL6063615 | 0.74 | ADK (0.82) | SLC29A1SLC28A1SLC28A2SLC28A3ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303282-A4 | PYRIDO[2,3-D]PYRIMIDINE AND PYRIMIDO[4,5-D]PYRIMIDINE NUCLEOSIDES | RIBAPHARM INC (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1303282-A1 | PYRIDO[2,3-D]PYRIMIDINE AND PYRIMIDO[4,5-D]PYRIMIDINE NUCLEOSIDES | Ribapharm, Inc. (US) | 2003-04-23 | — | — | EP | disclosed |
| WO-2002003997-A1 | PYRIDO[2,3-D]PYRIMIDINE AND PYRIMIDO[4,5-D]PYRIMIDINE NUCLEOSIDES | RIBAPHARM INC. (US) | 2002-01-17 | — | — | WO | disclosed |