Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 11/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3218235 | 0.91 | OPRM1 (0.53) | OPRL1OPRM1OPRK1OPRD1TAAR1 | |
| Hydrochloric Acid SCHEMBL3216972 | 0.90 | OPRM1 (0.54) | OPRL1OPRM1OPRK1OPRD1TAAR1 | |
| SCHEMBL3207955 | 0.76 | OPRM1 (0.64) | OPRL1OPRM1OPRK1OPRD1TAAR1 | |
| SCHEMBL3208044 | 0.76 | OPRM1 (0.68) | OPRL1OPRM1OPRK1OPRD1TAAR1 | |
| Hydrochloric Acid SCHEMBL3207516 | 0.75 | OPRM1 (0.65) | OPRL1OPRM1OPRK1OPRD1TAAR1 | |
| Hydrochloric Acid SCHEMBL3208779 | 0.75 | OPRM1 (0.68) | OPRL1OPRM1OPRK1OPRD1TAAR1 | |
| SCHEMBL3218308 | 0.72 | OPRM1 (0.41) | OPRL1OPRM1OPRK1 | |
| SCHEMBL23343753 | 0.72 | OPRL1 (0.65) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL3207969 | 0.70 | OPRM1 (0.56) | OPRL1OPRM1OPRK1OPRD1TAAR1 | |
| SCHEMBL3220333 | 0.70 | OPRM1 (0.56) | OPRL1OPRM1OPRK1OPRD1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406859-A1 | SUBSTITUTED 4-AMINOCYCLOHEXANOL DERIVATIVES | Grünenthal GmbH (DE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2003008371-A1 | SUBSTITUTED 4-AMINOCYCLOHEXANOL DERIVATIVES | Grünenthal GmbH (DE) | 2003-01-30 | — | — | WO | disclosed |