Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6570935 | 0.98 | MAPT (0.59) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL6572382 | 0.95 | HDAC1 (0.56) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL7450661 | 0.88 | ALDH1A1 (0.60) | HDAC1HDAC2SMN1; SMN2ALDH1A1HDAC3 | |
| SCHEMBL2440963 | 0.84 | MAPT (0.61) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL28508681 | 0.83 | HDAC1 (0.58) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL25834869 | 0.83 | MAPT (0.65) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL2625206 | 0.83 | MAPT (0.65) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL19130712 | 0.83 | MAPT (0.65) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL19130442 | 0.83 | MAPT (0.65) | MAPTRXFP1ALOX5HDAC1HDAC2 | |
| SCHEMBL12398374 | 0.83 | MAPT (0.65) | MAPTRXFP1ALOX5HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404325-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002096420-A2 | METHOD FOR TREATING NERVE INJURY CAUSED BY SURGERY | GUILFORD PHARMACEUTICALS INC. (US) | 2002-12-05 | — | — | WO | disclosed |
| WO-2001079177-A1 | CYCLIC DIAZA COMPOUNDS FOR TREATING NEURODEGENERATIVE DISORDERS | GPI NIL HOLDINGS, INC. (US) | 2001-10-25 | — | — | WO | disclosed |