Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331926 | 0.91 | MAP3K7 (0.65) | MAP3K7TAB1 | |
| SCHEMBL659878 | 0.88 | MAP3K7 (0.61) | MAP3K7TAB1 | |
| SCHEMBL657222 | 0.87 | MAP3K7 (0.59) | MAP3K7TAB1 | |
| SCHEMBL659404 | 0.86 | MAP3K7 (1.00) | MAP3K7TAB1 | |
| SCHEMBL657459 | 0.85 | MAP3K7 (1.00) | MAP3K7TAB1 | |
| SCHEMBL657458 | 0.85 | MAP3K7 (1.00) | MAP3K7TAB1 | |
| SCHEMBL659608 | 0.85 | MAP3K7 (1.00) | MAP3K7TAB1 | |
| SCHEMBL10217789 | 0.85 | MAP3K7 (0.81) | MAP3K7TAB1 | |
| SCHEMBL659858 | 0.85 | MAP3K7 (1.00) | MAP3K7TAB1 | |
| SCHEMBL10217798 | 0.84 | MAP3K7 (0.80) | MAP3K7TAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8378104-B2 | 7-aminofuropyridine derivatives | OSI Pharmaceuticals, LLC (US) | 2013-02-19 | — | — | US | disclosed |
| EP-2534156-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2012-12-19 | — | — | EP | disclosed |
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI PHARMACEUTICALS, INC. | 2012-02-23 | — | — | US | disclosed |
| WO-2011100502-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | OSI Pharmaceuticals, LLC (US) | 2011-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046267-A1 | 7-AMINOFUROPYRIDINE DERIVATIVES | MAP3K5, STK17A, MAPKAPK5 | MAP3K7 5/4885TAB1 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.