Di(Hydroxyethyl)Ether

Di(Hydroxyethyl)Ether

SCHEMBL6571535

NC(N)=O.OCCOCCO

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.67
MAPK1 P28482 1/20 0.67
MEN1 O00255 3/20 0.62
KMT2A Q03164 3/20 0.62
ALDH1A1 P00352 5/20 0.45
LMNA P02545 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
OR51E2 Q9H255 1/20 0.40
THRB P10828 1/20 0.40
HTT P42858 1/20 0.40
MAPT P10636 1/20 0.40
GAA P10253 1/20 0.37
APP P05067 1/20 0.32
TP53 P04637 3/20 0.31
HIF1A Q16665 2/20 0.31
HSD17B10 Q99714 2/20 0.31
ALOX15 P16050 2/20 0.30
KDM4E B2RXH2 1/20 0.30
GMNN O75496 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Triethylene Glycol SCHEMBL6398483 0.97 MEN1 (0.69) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL28461941 0.90 TSHR (0.62) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL11326327 0.90 TSHR (0.62) TSHRMAPK1MEN1KMT2AALDH1A1
Tetraethylene Glycol SCHEMBL1013721 0.88 KMT2A (0.65) TSHRMAPK1MEN1KMT2AALDH1A1
Triethylene Glycol SCHEMBL28296600 0.88 KMT2A (0.65) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL9491460 0.84 TSHR (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL9760937 0.84 TSHR (0.48) TSHRMAPK1MEN1KMT2AALDH1A1
SCHEMBL1848210 0.83
Di(Hydroxyethyl)Ether SCHEMBL27988744 0.83 TSHR (0.53) TSHRMAPK1MEN1KMT2AALDH1A1
Di(Hydroxyethyl)Ether SCHEMBL9273841 0.83 TSHR (0.71) TSHRMAPK1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1408091-A1 Disazo compound, dye, ink and ink-jet recording method FUJI PHOTO FILM CO., LTD. (JP) 2004-04-14 EP disclosed
US-20030020054-A1 FLAME RETARDANT COMPOSITIONS UTILIZING AMINO CONDENSATION COMPOUNDS BLOUNT DAVID H (US) 2003-01-30 US disclosed
US-6491850-B1 FOR RIGID INSULATING POLYURETHANE FOAM BLOUNT DAVID H (US) 2002-12-10 US disclosed
US-6270694-B1 PRODUCT FROM REACTED UREA, ORGANIC COMPOUND, WATER, CARBONIZATION AUXILIARIES, ALDEHYDE AND FILLER BLOUNT DAVID H (US) 2001-08-07 US disclosed