Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 15/20 | 0.71 |
| ▸ | PPARG | P37231 | 15/20 | 0.71 |
| ▸ | PPARD | Q03181 | 10/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.45 |
| ▸ | PSAT1 | Q9Y617 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5382121 | 0.91 | PPARA (0.71) | PPARAPPARGPPARDALDH1A1HTT | |
| SCHEMBL5377922 | 0.91 | PPARA (0.71) | PPARAPPARGPPARDALDH1A1HTT | |
| SCHEMBL6575428 | 0.89 | PPARA (0.58) | PPARAPPARGPPARDMAPT | |
| SCHEMBL6572125 | 0.89 | PPARA (0.58) | PPARAPPARGPPARDMAPT | |
| SCHEMBL6572905 | 0.89 | PPARA (0.57) | PPARAPPARGPPARDALDH1A1HTT | |
| SCHEMBL6574440 | 0.89 | PPARG (0.70) | PPARAPPARGPPARDSRRPSAT1 | |
| SCHEMBL6574322 | 0.89 | PPARA (0.70) | PPARAPPARGPPARDSRRPSAT1 | |
| SCHEMBL5377460 | 0.85 | PPARG (0.93) | PPARAPPARGPPARDALDH1A1HTT | |
| SCHEMBL5380859 | 0.85 | PPARG (0.93) | PPARAPPARGPPARDALDH1A1HTT | |
| SCHEMBL5381122 | 0.83 | PPARG (1.00) | PPARAPPARGPPARDALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | claimed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | claimed |
| EP-1392637-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2002100813-A2 | MODULATORS OF PEROXISOME PROLIFERATOR ACTIVATED RECEPTORS | ELI LILLY AND COMPANY (US) | 2002-12-19 | — | — | WO | disclosed |