Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 17/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 16/20 | 0.59 |
| ▸ | PDE4A | P27815 | 6/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.59 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4544198 | 0.83 | PDE4B (0.71) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2886497 | 0.83 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084827 | 0.83 | PDE4B (0.74) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL2887354 | 0.78 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL30084843 | 0.78 | PDE4D (0.68) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7065703 | 0.76 | PDE4A (0.54) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL27951573 | 0.75 | PDE4D (0.56) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL4163114 | 0.74 | PDE4B (0.77) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL7395863 | 0.74 | PDE4A (0.52) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL6571717 | 0.74 | PDE4D (0.61) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1429843-A2 | COMBINATION OF A PDE INHIBITOR AND A LEUKOTRIENE RECEPTOR ANTAGONIST | ALTANA Pharma AG (DE) | 2004-06-23 | — | — | EP | claimed |
| EP-1429807-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA Pharma AG (DE) | 2004-06-23 | — | — | EP | claimed |
| WO-2003024489-A2 | COMBINATION OF A NSAID AND A PDE-4 INHIBITOR | ALTANA PHARMA AG (DE) | 2003-03-27 | — | — | WO | claimed |
| WO-2003024488-A2 | COMBINATION OF A PDE INHIBITOR AND A LEUKOTRIENE RECEPTOR ANTAGONIST | ALTANA PHARMA AG (DE) | 2003-03-27 | — | — | WO | claimed |
| EP-1482938-A1 | PHARMACEUTICAL COMPOSITION OF A PDE4 OR A PDE3/4 INHIBITOR AND A HISTAMINE RECEPTOR ANTAGONIST | ALTANA Pharma AG (DE) | 2004-12-08 | — | — | EP | disclosed |
| WO-2003074055-A1 | PHARMACEUTICAL COMPOSITION OF A PDE4 OR A PDE3/4 INHIBITOR AND A HISTAMINE RECEPTOR ANTAGONIST | ALTANA PHARMA AG (DE) | 2003-09-12 | — | — | WO | disclosed |