Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 2/20 | 0.57 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.57 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954779 | 0.85 | CA1 (0.51) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL9512568 | 0.83 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL7431903 | 0.80 | SLC1A3 (0.50) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL28046230 | 0.79 | TTR (0.45) | SLC1A3SLC1A2SLC1A1NR4A1KYNU | |
| SCHEMBL27403973 | 0.77 | CA1 (0.58) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL28046229 | 0.77 | CA2 (0.59) | CA2F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8648359 | 0.75 | CA1 (0.55) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL4263471 | 0.75 | CA2 (0.55) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL10666079 | 0.74 | CA1 (0.53) | SLC1A3SLC1A2SLC1A1CA1CA2 | |
| SCHEMBL3245449 | 0.73 | CA1 (0.57) | SLC1A3SLC1A2SLC1A1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404340-A1 | NAPHTOTHIAZINE POSITIVE ALLOSTERIC AMPA RECEPTOR MODULATORS (PAARM) | Boehringer Ingelheim Pharma GmbH & Co.KG (DE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2002100411-A1 | NAPHTOTHIAZINE POSITIVE ALLOSTERIC AMPA RECEPTOR MODULATORS (PAARM) | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2002-12-19 | — | — | WO | disclosed |
| US-6127340-A | ESPCECIALLY THROMBIN, IN WHICH THE P1-P2 NATURAL AMIDE LINKAGE IS REPLACED BY ANOTHER BOND; INHIBITING COAGULATION OF BLOOD IN A CONTAINER; TREATMENT OR PREVENTION OF THROMBOSIS | TRIGEN LIMITED (GB) | 2000-10-03 | — | — | US | disclosed |
| EP-0809650-A1 | SERINE PROTEASE INHIBITORS | ELLERMAN PHARMACEUTICALS LIMITED (GB) | 1997-12-03 | — | — | EP | disclosed |
| WO-1996025427-A1 | SERINE PROTEASE INHIBITORS | ELLERMAN PHARMACEUTICALS LIMITED (GB) | 1996-08-22 | — | — | WO | disclosed |