Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 7/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 7/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1542065 | 0.86 | MEN1 (0.47) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL1542586 | 0.84 | GAA (0.47) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL2163290 | 0.84 | GAA (0.47) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL11761259 | 0.84 | GAA (0.56) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL10899332 | 0.82 | ALDH1A1 (0.45) | KMT2AFFAR1GAAKDM4EALDH1A1 | |
| SCHEMBL10900661 | 0.82 | FFAR1 (0.46) | MEN1KMT2AFFAR1SYKALDH1A1 | |
| SCHEMBL1542340 | 0.82 | GAA (0.46) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL1541994 | 0.82 | GAA (0.46) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL1391316 | 0.82 | GAA (0.57) | MEN1KMT2APDE4APDE4BPDE4C | |
| SCHEMBL1542314 | 0.82 | GAA (0.46) | MEN1KMT2APDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | DAVISON JOSHUA ZWICK (US) | 2004-07-29 | — | — | US | disclosed |
| EP-1409452-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002098846-A1 | SULFONAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147612-A1 | Sulfonamide derivatives | GRIN1, GRIN2A, GRIA1 | MEN1 4050/4885KMT2A 1168/4885PDE4A 3092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.