Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777675 | 0.85 | SMN1; SMN2 (0.36) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL34383 | 0.85 | SMN1; SMN2 (0.36) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL290461 | 0.85 | SMN1; SMN2 (0.40) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL1700762 | 0.85 | CYP1A2 (0.35) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL905722 | 0.83 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL4960230 | 0.83 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL379163 | 0.83 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL905700 | 0.83 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL1870550 | 0.83 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL905404 | 0.83 | SMN1; SMN2 (0.42) | KMT2ASMN1; SMN2PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816364-B1 | Reagents for lysergic acid diethylamide immunoassay | HOFFMANN LA ROCHE (CH) | 2004-01-02 | — | — | EP | claimed |
| EP-0863881-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-09-16 | — | — | EP | disclosed |
| WO-1997010219-A1 | BENZIMIDAZOLE DERIVATIVES AND THEIR USE IN THE PREVENTION AND/OR THE TREATMENT OF BONE DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-03-20 | — | — | WO | disclosed |