SCHEMBL1700762

SCHEMBL1700762

C#CCCCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.35
CYP2D6 P10635 2/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
HSD17B10 Q99714 1/20 0.35
CYP3A4 P08684 1/20 0.34
GSTP1 P09211 1/20 0.33
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALOX5 P09917 1/20 0.31
PTGS1 P23219 1/20 0.31
PTGS2 P35354 1/20 0.31
PSMB8 P28062 1/20 0.30
PSMB5 P28074 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1981540 0.95 CYP1A2 (0.42) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL596794 0.94 MAPT (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL26978299 0.94 MAPT (0.44) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL138410 0.90 PSMB8 (0.31) PSMB8PSMB5
SCHEMBL12101932 0.90 CYP1A2 (0.31) CYP1A2CYP2D6MAPTCYP2C9CYP2C19
SCHEMBL6572156 0.85 KMT2A (0.32) KMT2ASMN1; SMN2PSMB8PSMB5
SCHEMBL290461 0.84 SMN1; SMN2 (0.40) KMT2ASMN1; SMN2PSMB8PSMB5
SCHEMBL22777675 0.84 SMN1; SMN2 (0.36) KMT2ASMN1; SMN2PSMB8PSMB5
SCHEMBL34383 0.84 SMN1; SMN2 (0.36) KMT2ASMN1; SMN2PSMB8PSMB5
SCHEMBL905722 0.82 SMN1; SMN2 (0.42) KMT2ASMN1; SMN2PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025109631-A1 SYNTHETIC DELIVERY SYSTEMS AND CONJUGATES THEREOF MICRO CRISPR PVT. LTD. (IN) 2025-05-30 WO claimed
WO-2025109631-A1 SYNTHETIC DELIVERY SYSTEMS AND CONJUGATES THEREOF MICRO CRISPR PVT. LTD. (IN) 2025-05-30 WO disclosed
CN-119326907-A Coupling medicine and preparation method and application thereof 岩唐生物科技(杭州)有限责任公司 2025-01-21 CN disclosed
EP-2964658-B1 POSITRON-EMITTING SUBSTITUTED ORGANOFLUOROBORATES AS IMAGING AGENTS UNIV BRITISH COLUMBIA (CA) 2024-08-07 EP disclosed
WO-2024086633-A1 RNAI AGENTS FOR INHIBITING EXPRESSION OF DM1 PROTEIN KINASE (DMPK) COMPOSITIONS THEREOF, AND METHODS OF USE Arrowhead Pharmaceuticals, Inc. (US) 2024-04-25 WO disclosed
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
US-20230265430-A1 RNAi Agents for Inhibiting Expression of DUX4, Compositions Thereof, And Methods of Use SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT 2023-08-24 US disclosed
US-20230265430-A1 RNAi Agents for Inhibiting Expression of DUX4, Compositions Thereof, And Methods of Use SIXTH STREETLENDING PARTNERS, AS THE ADMINISTRATIVE AGENT 2023-08-24 US disclosed
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF Arrowhead Pharmaceuticals, Inc. 2023-08-24 US disclosed
CN-116622468-A Antifouling micro-bubble for biological orthogonal capture and preparation and application thereof 广西医科大学 2023-08-22 CN disclosed
EP-2591795-A1 RNA targeting compounds and methods for making and using same The Research Foundation Of State University Of New York (US) 2013-05-15 EP disclosed
EP-2566334-A1 CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS Prolynx Llc (US) 2013-03-13 EP disclosed
EP-2129388-B1 RNA TARGETING COMPOUNDS AND METHODS FOR MAKING AND USING SAME UNIV NEW YORK STATE RES FOUND 2012-09-12 EP disclosed
US-20120225089-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-09-06 US disclosed
US-20120225089-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF SANOFI (FR) 2012-09-06 US disclosed
WO-2011140392-A1 CONTROLLED DRUG RELEASE FROM SOLID SUPPORTS PROLYNX LLC (US) 2011-11-10 WO disclosed
US-20080227213-A1 Comprising polymer backbone and two or more pendant RNA binding ligands; myotonic dystrophy RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE 2008-09-18 US disclosed
US-20080227213-A1 Comprising polymer backbone and two or more pendant RNA binding ligands; myotonic dystrophy RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK, THE 2008-09-18 US disclosed
WO-2008103489-A2 RNA TARGETING COMPOUNDS AND METHODS FOR MAKING AND USING SAME THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) 2008-08-28 WO disclosed
US-20080188377-A1 Methods for identifying ligands that target nucleic acid molecules and nucleic acid structural motifs USA AS REPRESENTED BY THE ADMINISTRATOR OF THE NASA 2008-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120225089-A1 NOVEL CONJUGATES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF ERG28, CARS1, FOLH1 CYP1A2 1440/4885CYP2D6 1671/4885MAPT 2425/4885
US-20230265430-A1 RNAi Agents for Inhibiting Expression of DUX4, Compositions Thereof, And Methods of Use ZFX, DDX39B, DDX21 CYP1A2 4864/4885CYP2D6 4680/4885MAPT 3903/4885
US-20230265429-A1 SKELETAL MUSCLE DELIVERY PLATFORMS AND METHODS OF USE THEREOF MUSK, MYLK2, TNNC1 CYP1A2 4692/4885CYP2D6 1430/4885MAPT 4094/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.