Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.46 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3492496 | 0.98 | CYP4F2 (0.49) | CYP4F2CYP4A11MEN1KMT2APOLB | |
| SCHEMBL798044 | 0.92 | CYP4F2 (0.53) | CYP4F2CYP4A11MEN1KMT2APOLB | |
| SCHEMBL11345271 | 0.87 | CYP4F2 (0.49) | CYP4F2CYP4A11MEN1KMT2APOLB | |
| SCHEMBL8071102 | 0.87 | CYP4F2 (0.45) | CYP4F2CYP4A11MEN1KMT2APOLB | |
| SCHEMBL16639041 | 0.87 | LMNA (0.42) | MEN1KMT2APOLBPKMLMNA | |
| SCHEMBL882521 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1KMT2APOLB | |
| SCHEMBL798228 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1KMT2APOLB | |
| SCHEMBL798312 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1KMT2APOLB | |
| SCHEMBL798479 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1KMT2APOLB | |
| SCHEMBL798058 | 0.85 | CYP4F2 (0.47) | CYP4F2CYP4A11MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1455809-A2 | INHIBITORS OF HEPATITIS C VIRUS | Bristol-Myers Squibb Company (US) | 2004-09-15 | — | — | EP | disclosed |
| WO-2003053349-A2 | INHIBITORS OF HEPATITIS C VIRUS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-07-03 | — | — | WO | disclosed |