SCHEMBL6572374

SCHEMBL6572374

CC(=O)Nc1cc(N)ccc1OCCC[n+]1ccn(C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.38
CYP1A2 P05177 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
RAD52 P43351 1/20 0.36
GFER P55789 1/20 0.36
LMNA P02545 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
GAA P10253 2/20 0.33
NPC1 O15118 2/20 0.33
RAB9A P51151 1/20 0.33
TSHR P16473 1/20 0.32
BRD4 O60885 1/20 0.32
PPARD Q03181 1/20 0.32
PPARA Q07869 1/20 0.32
MGAT2 Q10469 1/20 0.32
HTT P42858 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
EPHX1 P07099 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL7635799 0.98 ALDH1A1 (0.39) ALDH1A1CYP1A2CYP2C9CYP2C19RAD52
SCHEMBL6571868 0.92 ALDH1A1 (0.38) ALDH1A1LMNASMN1; SMN2GAANPC1
Hydrochloric Acid SCHEMBL7251381 0.91 ALDH1A1 (0.39) ALDH1A1LMNASMN1; SMN2GAANPC1
SCHEMBL2929052 0.85 RAD52 (0.37) ALDH1A1CYP1A2CYP2C9RAD52GFER
Hydrochloric Acid SCHEMBL6573509 0.85 RAD52 (0.36) ALDH1A1CYP1A2CYP2C9RAD52GFER
SCHEMBL6572085 0.84 SMN1; SMN2 (0.44) ALDH1A1LMNASMN1; SMN2RAB9AHTT
Hydrochloric Acid SCHEMBL7642086 0.83 SMN1; SMN2 (0.44) ALDH1A1LMNASMN1; SMN2RAB9AHTT
SCHEMBL6572111 0.81 ALDH1A1 (0.36) ALDH1A1LMNASMN1; SMN2GAANPC1
SCHEMBL2930165 0.81 MAPT (0.49) ALDH1A1CYP1A2CYP2C9CYP2C19GAA
Hydrochloric Acid SCHEMBL7969957 0.81 ALDH1A1 (0.38) ALDH1A1LMNASMN1; SMN2GAANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1064267-B1 NOVEL CATIONIC COUPLING AGENTS, THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS OREAL (FR) 2004-09-29 EP disclosed
EP-1064267-A1 NOVEL CATIONIC COUPLING AGENTS, THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS L'OREAL (FR) 2001-01-03 EP disclosed
WO-1999048874-A1 NOVEL CATIONIC COUPLING AGENTS, THEIR USE FOR OXIDATION DYEING OF KERATINOUS FIBRES, DYEING COMPOSITIONS AND DYEING METHODS L'OREAL (FR) 1999-09-30 WO disclosed