Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 15/20 | 0.80 |
| ▸ | RARB | P10826 | 14/20 | 0.80 |
| ▸ | RARA | P10276 | 12/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | TP53 | P04637 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | HPGD | P15428 | 1/20 | 0.72 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.72 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.72 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6571308 | 0.89 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL174205 | 0.84 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8766318 | 0.84 | RARG (0.77) | RARGRARBRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29727107 | 0.84 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29357074 | 0.84 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29357288 | 0.84 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL5081688 | 0.84 | RARG (0.67) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL444659 | 0.83 | RARG (0.76) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL13285215 | 0.83 | RARG (0.76) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8767120 | 0.82 | RARG (0.71) | RARGRARBRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0920312-B1 | APOPTOSIS INDUCING ADAMANTYL DERIVATIVES AND THEIR USAGE AS ANTI-CANCER AGENTS | GALDERMA RES & DEV (FR) | 2004-12-08 | — | — | EP | claimed |