Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARG | P13631 | 14/20 | 0.76 |
| ▸ | RARB | P10826 | 13/20 | 0.76 |
| ▸ | RARA | P10276 | 12/20 | 0.76 |
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.76 |
| ▸ | TP53 | P04637 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.76 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.76 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.73 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14960845 | 0.87 | RARB (0.62) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL28598962 | 0.87 | RARG (0.54) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL25870579 | 0.86 | MEN1 (0.76) | RARGRARBRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29727107 | 0.86 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29357074 | 0.86 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL29357288 | 0.86 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| O-Demethylated Adapalene SCHEMBL174205 | 0.86 | RARG (1.00) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL8766318 | 0.86 | RARG (0.77) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL6535711 | 0.85 | RARG (0.83) | RARGRARBRARAMEN1KMT2A | |
| SCHEMBL13285215 | 0.85 | RARG (0.76) | RARGRARBRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11707442-B2 | Antibacterial and antifungal compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-25 | — | — | US | disclosed |
| US-8907109-B2 | Methods and systems for treating cell proliferation disorders with psoralen derivatives | IMMUNOLIGHT, LLC (US) | 2014-12-09 | — | — | US | disclosed |
| US-8791275-B2 | Methods and systems for treating cell proliferation disorders with psoralen derivatives | DUKE UNIVERSITY (US) | 2014-07-29 | — | — | US | disclosed |
| US-20130129757-A1 | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS WITH PSORALEN DERIVATIVES | IMMUNOLIGHT, LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-20130131429-A1 | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS WITH PSORALEN DERIVATIVES | lmmunolight, LLC (US) | 2013-05-23 | — | — | US | disclosed |
| US-8278332-B2 | Photostabilization of retinoids with alkoxycrylene compounds | HALLSTAR INNOVATIONS CORP. (US) | 2012-10-02 | — | — | US | disclosed |
| US-8268294-B2 | Photostabilization of retinoids with alkoxycrylene compounds | HALLSTAR INNOVATIONS CORP. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20120065232-A1 | PHOTOSTABILIZATION OF RETINOIDS WITH ALKOXYCRYLENE COMPOUNDS | HALLSTAR INNOVATIONS CORP. (US) | 2012-03-15 | — | — | US | disclosed |
| US-20110142771-A1 | Photostabilization of Retinoids with Alkoxycrylene Compounds | HALLSTAR INNOVATIONS CORP. (US) | 2011-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142771-A1 | Photostabilization of Retinoids with Alkoxycrylene Compounds | RBP4, RARA, RBP1 | RARG 6/4885RARB 4/4885RARA 2/4885 |
| US-11707442-B2 | Antibacterial and antifungal compounds | RXRA, VDR, RXRB | RARG 14/4885RARB 9/4885RARA 8/4885 |
| US-20130131429-A1 | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS WITH PSORALEN DERIVATIVES | CDK20, NFATC1, CDK10 | RARG 765/4885RARB 899/4885RARA 440/4885 |
| US-20130129757-A1 | METHODS AND SYSTEMS FOR TREATING CELL PROLIFERATION DISORDERS WITH PSORALEN DERIVATIVES | CDK20, NFATC1, CDK10 | RARG 765/4885RARB 899/4885RARA 440/4885 |
| US-20120065232-A1 | PHOTOSTABILIZATION OF RETINOIDS WITH ALKOXYCRYLENE COMPOUNDS | RBP4, RARA, RBP1 | RARG 6/4885RARB 4/4885RARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.