Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575094 | 0.88 | ADORA3 (0.49) | ADORA3ADORA2AADORA2BADORA1DOT1L | |
| SCHEMBL6576915 | 0.84 | ADORA2A (0.61) | ADORA3ADORA2AADORA2BADORA1PMP22 | |
| SCHEMBL6574448 | 0.83 | ADORA1 (0.64) | ADORA3ADORA2AADORA2BADORA1PMP22 | |
| SCHEMBL6573028 | 0.83 | TYMP (0.48) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6575155 | 0.81 | ADORA3 (0.46) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6575157 | 0.81 | ADORA3 (0.46) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6574533 | 0.79 | ADORA1 (0.53) | ADORA3ADORA2AADORA2BADORA1PMP22 | |
| SCHEMBL6574536 | 0.79 | ADORA1 (0.53) | ADORA3ADORA2AADORA2BADORA1PMP22 | |
| SCHEMBL6575138 | 0.79 | ADORA3 (0.64) | ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL6572956 | 0.79 | ADORA3 (0.58) | ADORA3ADORA2AADORA2BADORA1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |