Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CDC25C | P30307 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575856 | 0.84 | KCNH2 (0.56) | KCNH2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6575943 | 0.83 | CYP1A2 (0.56) | KCNH2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL24900403 | 0.83 | SMN1; SMN2 (0.52) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6571816 | 0.82 | BLM (0.57) | KCNH2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6574454 | 0.82 | MAPT (0.60) | KCNH2KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL6571843 | 0.82 | CYP1A2 (0.55) | KCNH2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL6573041 | 0.82 | CYP1A2 (0.55) | KCNH2MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL30957607 | 0.81 | SMN1; SMN2 (0.52) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL24900749 | 0.81 | SMN1; SMN2 (0.52) | MEN1KMT2AMAPTSMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6573751 | 0.81 | BLM (0.56) | KCNH2MEN1KMT2AMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775689-B9 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2004-09-15 | — | — | EP | disclosed |
| EP-0775689-B1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RES LABS (KR) | 2003-09-03 | — | — | EP | disclosed |
| US-6057358-A | POTASSIUM CHANNEL BLOCKING ANTIARRHYTHMIC DRUGS WITH LESS SIDE EFFECTS | C&C RESEARCH LABS. (KR) | 2000-05-02 | — | — | US | disclosed |
| EP-0775689-A1 | NOVEL AMINE DERIVATIVE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF AS ANTIARRHYTHMIC | C & C RESEARCH LABS. (KR) | 1997-05-28 | — | — | EP | disclosed |