SCHEMBL6572896

SCHEMBL6572896

C=CCO[PH](=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30384 0.77
SCHEMBL28931612 0.74
Ammonia Solution, Strong SCHEMBL29217970 0.74
SCHEMBL7175038 0.74
SCHEMBL877782 0.72
SCHEMBL971458 0.72
SCHEMBL10713374 0.72
SCHEMBL30887 0.72
SCHEMBL8769381 0.72
SCHEMBL10511144 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108025298-B FCC catalyst additives and binders 雅宝公司 2021-07-06 CN disclosed
EP-0642507-B1 TRANSITION STATE ANALOGUES OF COCAINE, THEIR USE FOR PRODUCING CATALYTIC ANTIBODIES AGAINST COCAINE AND USE OF THE SAME IN DIAGNOSIS AND THERAPY UNIV COLUMBIA (US) 2004-02-04 EP disclosed
US-6566084-B1 Detecting hydrolysis of cocaine compound; obtain cocaine mixture, incubate with antibody, monitor generation of benzoic zacid THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK 2003-05-20 US disclosed
US-5990285-A ANTIBODY CAPABLE OF BINDING A TRANSITION STATE ANALOG FOR THE HYDROLYSIS OF COCAINE BENZOYL ESTER GROUP; TREATMENT OF DRUG ABUSE, DRUG DEPENDENCE, OVERDOSES THE TRUSTEES OF COLUMBIA UNIVERSITY (US) 1999-11-23 US disclosed
US-5977314-A ANTIBODY CAPABLE OF CATALYZING THE HYDROLYSIS OF COCAINE AT BENZOYL ESTER GROUP AND AGAINST SPECIFIC STRUCTURAL COMPOUNDS LISTED; FOR DECREASING CONCENTRATION OF COCAINE IN A SUBJECT THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-11-02 US disclosed
US-5463028-A Compound comprising a methyl ecgonine group chemically attached to a phenylphosphonic group which is an analog to an intermediate of the hydrolysis transition-state of a cocaine benzoyl ester group THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1995-10-31 US disclosed
EP-0642507-A4 CATALYTIC ANTIBODIES AGAINST COCAINE AND METHODS OF USING AND PRODUCING SAME. 1995-03-29 EP disclosed
EP-0642507-A1 CATALYTIC ANTIBODIES AGAINST COCAINE AND METHODS OF USING AND PRODUCING SAME The Trustees of Columbia University in the City of New York (US) 1995-03-15 EP disclosed
WO-1993020076-A1 CATALYTIC ANTIBODIES AGAINST COCAINE AND METHODS OF USING AND PRODUCING SAME THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1993-10-14 WO disclosed
EP-0343897-A1 Seawater-insoluble hydrolysable polymers and marine anti-fouling paint containing them COURTAULDS COATINGS (HOLDINGS) LIMITED (GB) 1989-11-29 EP disclosed