SCHEMBL6572929

SCHEMBL6572929

Nc1cc(O)c(NC(=O)Cn2cc[n+](CC(=O)Nc3cc(Cl)c(N)cc3O)c2)cc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 3/20 0.38
HPGD P15428 3/20 0.38
LMNA P02545 2/20 0.38
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
RECQL P46063 1/20 0.36
POLB P06746 3/20 0.36
HTT P42858 2/20 0.35
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
CA1 P00915 4/20 0.34
CA2 P00918 4/20 0.34
CYP2D6 P10635 2/20 0.33
STAT3 P40763 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
TSHR P16473 1/20 0.33
CA4 P22748 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL6572782 0.99 MAPK1 (0.38) MAPK1HPGDLMNAMEN1KMT2A
SCHEMBL6572100 0.87 HPGD (0.43) MAPK1HPGDLMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL6572664 0.86 HPGD (0.42) MAPK1HPGDLMNAMEN1KMT2A
SCHEMBL6937070 0.86 HPGD (0.41) MAPK1HPGDLMNAPOLBHTT
SCHEMBL6573660 0.85 KMT2A (0.34) MAPK1HPGDLMNAMEN1KMT2A
SCHEMBL6572876 0.85 LMNA (0.39) MAPK1HPGDLMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL6938864 0.85 LMNA (0.40) MAPK1HPGDLMNAPOLBHTT
Hydrochloric Acid SCHEMBL6573898 0.84 POLB (0.40) MAPK1HPGDLMNAMEN1KMT2A
Hydrochloric Acid SCHEMBL6572968 0.84 POLB (0.35) MAPK1HPGDLMNAMEN1KMT2A
SCHEMBL6573686 0.83 RAD52 (0.39) MAPK1HPGDLMNAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066263-B1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS OREAL (FR) 2004-05-26 EP claimed
EP-1066263-B1 NOVEL CATIONIC 2-ACYLAMINOPHENOLS, THEIR USE AS COUPLER FOR OXIDATION DYEING, COMPOSITIONS CONTAINING THEM, AND DYEING METHODS OREAL (FR) 2004-05-26 EP disclosed